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Encephalopathy, Stroke, and Myocardial Infarction With DMSO Use in Stem Cell Transplantation
Neurol 68:859-861, Chen-Plotkin,A.S.,et al, 2007
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Article Abstract
Stem cell transplants are established therapy for hematologic and solid tumor malignancies. Known neurological complications of stem cell transplantation include CNS infection, seizures, strokes, metabolic encephalopathy, and hemorrhage. We report two cases of autologous stem cell transplantation complicated by cerebral infarction and myocardial injury. We postulate that the cryopreservative dimethyl sulfoxide may be responsible.
 
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cerebrovascular accident
cryopreservation
dimethylsulfoxide
encephalopathy
myocardial infarction
myocardial injury
stem cell transplantation

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